GSK-2334470 ((3S)

Name: GSK-2334470 ((3S); MyBioSource
Brand: MyBioSource
SKU: MBS847928
Price: 295 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS847928

GSK-2334470 is a highly specific and potent inhibitor of PDK1 (3-Phosphoinositide dependent protein kinase-1) (IC50 = 10 nM). It does not suppress activity on other 96 kinases, including Aurora, ROCK, p38 MAPK and PI3K. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

GSK-2334470, Biochemical

Full Product Name

GSK-2334470

Product Synonym Names

(3S; 6R)-1-[6- (3-Amino-1H-indazol-6-yl)-2- (methylamino)-4-pyrimidinyl]-N-cyclohexyl-6-methyl-3-piperidinecarboxamide

Form/Format

Light yellow solid

Purity/Purification

>=98% by HPLC

Preparation and Storage

Store at -20 degree C
Protect from air and light
Shelf life: ~36 months

Molecular Weight

462.59

Solubility

DMSO (>40 mg/ml) or EtOH (>30 mg/ml)

Molecular Formula

C??H??N?O

CAS Number

1227911-45-6

PubChem CID

46215815

SMILES

CC1CCC (CN1C2=NC (=NC (=C2)C3=CC4=C (C=C3)C (=NN4)N)NC)C (=O)NC5CCCCC5

InChi

InChI=1S/C25H34N8O/c1-15-8-9-17 (24 (34)28-18-6-4-3-5-7-18)14-33 (15)22-13-20 (29-25 (27-2)30-22)16-10-11-19-21 (12-16)31-32-23 (19)26/h10-13,15,17-18H,3-9,14H2,1-2H3, (H,28,34)(H3,26,31

InChi Key

QLPHOXTXAKOFMU-WBVHZDCISA-N

Product Categories/Family for GSK-2334470 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; Phosphoinositide; dependent kinase 1 (PDK1)Inhibitors; Enzyme Inhibitors (A-Z); Biochemicals; Biochemicals (A-Z)

Product References and Citations for GSK-2334470 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/46215815

Other Notes

Small volumes of GSK-2334470 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GSK-2334470 purchase

MBS847928 is a biochemical targeting GSK-2334470.