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LCL161

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS847972

MBS847972 is a biochemical targeting LCL161. A SMAC mimetic, potently binds to and inhibits multiple IAPs (i.e. XIAP, c-IAP) More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
LCL161, Biochemical
Full Product Name
LCL161
Product Synonym Names
LCL-161; lcl161; (2S)-N-[ (1S)-1-cyclohexyl-2-[ (2S)-2-[4- (4-fluorobenzoyl)-1; 3-thiazol-2-yl]pyrrolidin-1-yl]-2-oxoethyl]-2- (methylamino) propenamide; XIAP Inhibitor; IAP inhibitor
Form/Format
White solid powder
Purity/Purification
99.72%by HPLC
Preparation and Storage
Store at -20 degree C
Protect from air and light
Shelf life: ~36 months
Molecular Weight
500.63
Solubility
Ethanol: 20 mg/ml warmed (39.94 mM)
DMSO: 100 mg/ml (199.74 mM)
Molecular Formula
C26H33FN4O3S
CAS Number
1005342-46-0
MDL Number
MFCD23160049
PubChem CID
24737642
SMILES
CC (C (=O)NC (C1CCCCC1)C (=O)N2CCCC2C3=NC (=CS3)C (=O)C4=CC=C (C=C4)F)NC
InChi
1S/C26H33FN4O3S/c1-16 (28-2)24 (33)30-22 (17-7-4-3-5-8-17)26 (34)31-14-6-9-21 (31)25-29-20 (15-35-25)23 (32)18-10-12-19 (27)13-11-18/h10-13,15-17,21-22,28H,3-9,14H2,1-2H3, (H,30,33)/t16-,21-,22-/m0/s1
InChi Key
UFPFGVNKHCLJJO-SSKFGXFMSA-N

Product Categories/Family for LCL161 biochemical

Enzyme Inhibitors; Other Inhibitors; Biochemicals; Enzyme Inhibitors; Apoptosis & Related Products; Apoptosis Inducers; Biochemicals; Biochemicals (A-Z)

Structure of LCL161 biochemical

LCL161 Biochemical – Cat# MBS847972

Product References and Citations for LCL161 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/24737642#section=Top

Other Notes

Small volumes of LCL161 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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