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AMG-Tie2

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS847982

MBS847982 is a biochemical targeting AMG-Tie2. AMG-Tie2 is a highly potent, non-selective inhibitor of Tie-2 More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
AMG-Tie2, Biochemical
Full Product Name
AMG-Tie2
Product Synonym Names
AMGTie2; AMG Tie2; 4-methyl-3-[3-[2- (methylamino) pyrimidin-4-yl]pyridin-2-yl]oxy-N-[3- (trifluoromethyl) phenyl]benzamide; Tie-2 inhibitor; Tie2 inhibitor
Form/Format
Solid
Purity/Purification
>=98%
Preparation and Storage
Store at -20 degree C
Protect from air and light
Shelf life: ~36 months
Molecular Weight
479.4
Solubility
DMSO (15 mM)
Molecular Formula
C??H??F?N?O?
CAS Number
870223-96-4
MDL Number
MFCD16038641
PubChem CID
16108977
SMILES
CC1=C (C=C (C=C1)C (=O)NC2=CC=CC (=C2)C (F)(F)F)OC3=C (C=CC=N3)C4=NC (=NC=C4)NC
InChi
1S/C25H20F3N5O2/c1-15-8-9-16 (22 (34)32-18-6-3-5-17 (14-18)25 (26,27)28)13-21 (15)35-23-19 (7-4-11-30-23)20-10-12-31-24 (29-2)33-20/h3-14H,1-2H3, (H,32,34)(H,29,31,33)
InChi Key
ZVIWALRWYYSHSU-UHFFFAOYSA-N

Product Categories/Family for AMG-Tie2 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Tyrosine Kinase Inhibitors; Enzyme Inhibitors (A-Z); Signaling Pathways; EGFR Signaling; EGFR Inhibitors; Cancer Research; Oncogenic Signaling Pathway; Biochemicals; Biochemicals (A-Z)

Structure of AMG-Tie2 biochemical

AMG-Tie2 Biochemical – Cat# MBS847982

Product References and Citations for AMG-Tie2 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/16108977#section=Top

Other Notes

Small volumes of AMG-Tie2 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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