Lonafarnib (Sarasar)

Name: Lonafarnib (Sarasar); MyBioSource
Brand: MyBioSource
SKU: MBS847986
Price: 305 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS847986

Lonafarnib (SCH 66336) is a selectively farnesyltransferase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM, respectively. More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Lonafarnib, Biochemical

Full Product Name

Lonafarnib

Product Synonym Names

Sarasar; SCH 66336; SCH66336; SCH-66336; 4- (2- (4- (8-Chloro-3; 10-dibromo-6; 11-dihydro-5H-benzo (5; 6) cyclohepta (1; 2-b) pyridin-11-yl)-1-piperidinyl)-2-oxoethyl)-1-piperidinecarboxamide; farnesyltransferase inhibitor; FTI inhibitor

Form/Format

Solid powder

Purity/Purification

>98%

Preparation and Storage

Store at -20 degree C
Protect from air and light
Shelf life: ~36 months

Molecular Weight

638.82

Solubility

DMSO (127 mg/mL
198.8 mM)

Molecular Formula

C??H??Br?ClN?O?

CAS Number

193275-84-2

MDL Number

MFCD06795138

PubChem CID

148195

SMILES

C1CN (CCC1CC (=O)N2CCC (CC2)C3C4=C (C=C (C=C4CCC5=CC (=CN=C35)Br)Cl)Br)C (=O)N

InChi

1S/C27H31Br2ClN4O2/c28-20-12-19-2-1-18-13-21 (30)14-22 (29)24 (18)25 (26 (19)32-15-20)17-5-9-33 (10-6-17)23 (35)11-16-3-7-34 (8-4-16)27 (31)36/h12-17,25H,1-11H2, (H2,31,36)/t25-/m1/s1

InChi Key

DHMTURDWPRKSOA-RUZDIDTESA-N

Product Categories/Family for Lonafarnib biochemical

Enzyme Inhibitors; Farnesyl Protein Transferase (FPT) Inhibitors; Enzyme Inhibitors (A-Z); Biochemicals; Biochemicals (A-Z)

Product References and Citations for Lonafarnib biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/148195

Other Notes

Small volumes of Lonafarnib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Lonafarnib purchase

MBS847986 is a biochemical targeting Lonafarnib.