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BMS-708163

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS847990

BMS-708163 is a potent, selective gamma-secretase inhibitor of Abeta40 and Abeta42 with IC50 of 0.3 nM and 0.27 nM, respectively More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
BMS-708163, Biochemical
Full Product Name
BMS-708163
Product Synonym Names
BMS-708163; BMS708163; BMS 708163; Avagacestat; gamma-secretase inhibitor; (2R)-2- (N- (2-fluoro-4- (1; 2; 4-oxadiazol-3-yl) benzyl)-4-chlorophenylsulfonamido)-5; 5; 5-trifluoropentanamide
Form/Format
White solid powder
Purity/Purification
>98%
Preparation and Storage
Store at -20 degree C
Protect from air and light
Shelf life: ~36 months
Molecular Weight
520.88
Solubility
DMSO> 10 mM
Molecular Formula
C??H??ClF?N?O?S
CAS Number
1146699-66-2
MDL Number
MFCD13195458
PubChem CID
46883536
SMILES
C1=CC (=CC=C1S (=O)(=O)N (CC2=C (C=C (C=C2)C3=NOC=N3)F)C (CCC (F)(F)F)C (=O)N)Cl
InChi
1S/C20H17ClF4N4O4S/c21-14-3-5-15 (6-4-14)34 (31,32)29 (17 (18 (26)30)7-8-20 (23,24)25)10-13-2-1-12 (9-16 (13)22)19-27-11-33-28-19/h1-6,9,11,17H,7-8,10H2, (H2,26,30)/t17-/m1/s1
InChi Key
XEAOPVUAMONVLA-QGZVFWFLSA-N

Product Categories/Family for BMS-708163 biochemical

Biochemicals; Enzyme Inhibitors; Secretase Inhibitors; Stem Cell Research Tools; Stem Cell Fate Regulators; Differentiation; Biochemicals (A-Z)

Structure of BMS-708163 biochemical

BMS-708163 Biochemical – Cat# MBS847990

Product References and Citations for BMS-708163 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/46883536

Other Notes

Small volumes of BMS-708163 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BMS-708163 purchase

MBS847990 is a biochemical targeting BMS-708163.
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