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CH5183284

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848015

CH5183284 is a selective and orally available FGFR1/2/3 inhibitor. The IC50 values of CH5183284 on the enzyme activity of FGFR1/2/3/4 were 9.3, 7.6, 22, and 290 nM, respectively. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
CH5183284, Biochemical
Full Product Name
CH5183284
Product Synonym Names
CH5183284; CH-5183284; CH 5183284; Debio-1347; Debio 1347; Debio1347; FF284; FF-284; FF 284; (5-amino-1- (2-methyl-1H-benzo[d]imidazol-6-yl)-1H-pyrazol-4-yl) (1H-indol-2-yl) methanone
Form/Format
Solid powder
Purity/Purification
>98%
Preparation and Storage
Store at -20 degree C
Protect from air and light
Shelf life: ~36 months
Molecular Weight
356.38
Solubility
DMSO
Molecular Formula
C??H??N?O
CAS Number
1265229-25-1
PubChem CID
66555680
SMILES
CC1=NC2=C (N1)C=C (C=C2)N3C (=C (C=N3)C (=O)C4=CC5=CC=CC=C5N4)N
InChi
InChI=1S/C20H16N6O/c1-11-23-16-7-6-13 (9-17 (16)24-11)26-20 (21)14 (10-22-26)19 (27)18-8-12-4-2-3-5-15 (12)25-18/h2-10,25H,21H2,1H3, (H,23,24)
InChi Key
BEMNJULZEQTDJY-UHFFFAOYSA-N

Product Categories/Family for CH5183284 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Tyrosine Kinase Inhibitors; Enzyme Inhibitors (A-Z); Signaling Pathways; EGFR Signaling; EGFR Inhibitors; Cancer Research; Oncogenic Signaling Pathway; Biochemicals; Biochemicals (A-Z)

Structure of CH5183284 biochemical

CH5183284 Biochemical – Cat# MBS848015

Product References and Citations for CH5183284 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/66555680

Other Notes

Small volumes of CH5183284 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CH5183284 purchase

MBS848015 is a biochemical targeting CH5183284.
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