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BLZ-945

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848017

BLZ945 is a brain-penetrant CSF-1R kinase inhibitor. The biochemical IC50 for CSF-1R is 1 nM, which is >3200-fold higher than its affinity for other kinases. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
BLZ-945, Biochemical
Full Product Name
BLZ-945
Product Synonym Names
BLZ-945; BLZ945; BLZ 945; 4- ( (2- ( ( (1R; 2R)-2-hydroxycyclohexyl) amino) benzo[d]thiazol-6-yl) oxy)-N-methylpicolinamide; 4-[[2-[[ (1R; 2R)-2-hydroxycyclohexyl]amino]-1; 3-benzothiazol-6-yl]oxy]-N-methylpyridine-2-carboxamide
Form/Format
Solid powder
Purity/Purification
>98%
Preparation and Storage
Store at -20 degree C
Protect from air and light
Shelf life: ~36 months
Molecular Weight
398.48
Solubility
DMSO
Molecular Formula
C??H??N?O?S
CAS Number
953769-46-5
MDL Number
MFCD28142668
PubChem CID
46184986
SMILES
CNC (=O)C1=NC=CC (=C1)OC2=CC3=C (C=C2)N=C (S3)NC4CCCCC4O
InChi
InChI=1S/C20H22N4O3S/c1-21-19 (26)16-10-13 (8-9-22-16)27-12-6-7-15-18 (11-12)28-20 (24-15)23-14-4-2-3-5-17 (14)25/h6-11,14,17,25H,2-5H2,1H3, (H,21,26)(H,23,24)/t14-,17-/m1/s1
InChi Key
ADZBMFGQQWPHMJ-RHSMWYFYSA-N

Product Categories/Family for BLZ-945 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Tyrosine Kinase Inhibitors; Enzyme Inhibitors (A-Z); Signaling Pathways; EGFR Signaling; EGFR Inhibitors; Cancer Research; Oncogenic Signaling Pathway; Biochemicals; Biochemicals (A-Z)

Structure of BLZ-945 biochemical

BLZ-945 Biochemical – Cat# MBS848017

Product References and Citations for BLZ-945 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/46184986#section=Top

Other Notes

Small volumes of BLZ-945 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BLZ-945 purchase

MBS848017 is a biochemical targeting BLZ-945.
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