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SB-590885

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848067

SB590885 is a potent B-Raf inhibitor with Ki of 0.16 nM, 11-fold greater selectivity for B-Raf over c-Raf, no inhibition to other human kinases. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
SB-590885, Biochemical
Full Product Name
SB-590885
Product Synonym Names
SB-590885; SB590885; SB 590885; (E)-5- (2- (4- (2- (dimethylamino) ethoxy) phenyl)-5- (pyridin-4-yl)-1H-imidazol-4-yl)-2; 3-dihydro-1H-inden-1-one oxime; N; N-dimethyl-2-[4-[ (4Z)-4- (1-nitroso-2; 3-dihydroinden-5-ylidene)-5- (1H-pyridin-4-ylidene)-1H-imidazol-2-yl]phenoxy]ethanamine
Form/Format
Solid powder
Purity/Purification
>98%
Preparation and Storage
Store at -20 degree C
Protect from air and light
Shelf life: ~36 months
Molecular Weight
453.54
Solubility
DMSO
Molecular Formula
C??H??N?O?
CAS Number
405554-55-4
PubChem CID
11465183
SMILES
CN (C)CCOC1=CC=C (C=C1)C2=NC (=C3C=CC4=C (CCC4=C3)N=O)C (=C5C=CNC=C5)N2
InChi
InChI=1S/C27H27N5O2/c1-32 (2)15-16-34-22-7-3-19 (4-8-22)27-29-25 (18-11-13-28-14-12-18)26 (30-27)21-5-9-23-20 (17-21)6-10-24 (23)31-33/h3-5,7-9,11-14,17,28H,6,10,15-16H2,1-2H3, (H,29,30)/b26-21+
InChi Key
DPCXEUSDRQOOGZ-YYADALCUSA-N

Product Categories/Family for SB-590885 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; Raf Kinase Inhibitors; Biochemicals; Biochemicals (A-Z)

Structure of SB-590885 biochemical

Sb-590885 Biochemical – Cat# MBS848067

Product References and Citations for SB-590885 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/11465183#section=Top

Other Notes

Small volumes of SB-590885 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SB-590885 purchase

MBS848067 is a biochemical targeting SB-590885.
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