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L-779450

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848068

L-779450 is a potent, ATP-competitive Raf kinase inhibitor (IC50 =10 nM) that displays > 7, > 30 and > 70-fold selectivity over p38alpha, GSK3beta and Lck respectively. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
L-779450, Biochemical
Full Product Name
L-779450
Product Synonym Names
L-779450; L779450; L 779450; 2-chloro-5- (2-phenyl-5- (pyridin-4-yl)-1H-imidazol-4-yl) phenol
Form/Format
Solid powder
Purity/Purification
>98%
Preparation and Storage
Store at -20 degree C
Protect from air and light
Shelf life: ~36 months
Molecular Weight
347.8
Solubility
DMSO
Molecular Formula
C??H??ClN?O
CAS Number
303727-31-3
PubChem CID
9950176
SMILES
C1=CC=C (C=C1)C2=NC (=C (N2)C3=CC=NC=C3)C4=CC (=C (C=C4)Cl)O
InChi
InChI=1S/C20H14ClN3O/c21-16-7-6-15 (12-17 (16)25)19-18 (13-8-10-22-11-9-13)23-20 (24-19)14-4-2-1-3-5-14/h1-12,25H, (H,23,24)
InChi Key
WXJLXRNWMLWVFB-UHFFFAOYSA-N

Product Categories/Family for L-779450 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; Raf Kinase Inhibitors; Biochemicals; Biochemicals (A-Z)

Structure of L-779450 biochemical

L-779450 Biochemical – Cat# MBS848068

Product References and Citations for L-779450 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/9950176#section=Top

Other Notes

Small volumes of L-779450 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for L-779450 purchase

MBS848068 is a biochemical targeting L-779450.
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