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PKI-402

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848074

PKI-402 is a reversible, potent dual inhibitor of PI3K/mTOR with IC50 values of 2 nM/7 nM/16 nM/14 nM and 3 nM for PI3Kalpha/beta/gamma/delta and mTOR, respectively. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PKI-402, Biochemical
Full Product Name
PKI-402
Product Synonym Names
PKI-402; PKI 402; PKI402; 1-[4- (3-ethyl-7-morpholin-4-yltriazolo[4; 5-d]pyrimidin-5-yl) phenyl]-3-[4- (4-methylpiperazine-1-carbonyl) phenyl]urea
Form/Format
Solid powder
Purity/Purification
>98%
Preparation and Storage
Store at -20 degree C
Protect from air and light
Shelf life: ~36 months
Molecular Weight
570.65
Solubility
DMSO
Molecular Formula
C??H??N??O?
CAS Number
173204-81-3
MDL Number
MFCD18251484
PubChem CID
44187953
SMILES
CCN1C2=C (C (=NC (=N2)C3=CC=C (C=C3)NC (=O)NC4=CC=C (C=C4)C (=O)N5CCN (CC5)C)N6CCOCC6)N=N1
InChi
InChI=1S/C29H34N10O3/c1-3-39-27-24 (34-35-39)26 (37-16-18-42-19-17-37)32-25 (33-27)20-4-8-22 (9-5-20)30-29 (41)31-23-10-6-21 (7-11-23)28 (40)38-14-12-36 (2)13-15-38/h4-11H,3,12-19H2,1-2H3, (H2,30,31,41)
InChi Key
ZAXFYGBKZSQBIV-UHFFFAOYSA-N

Product Categories/Family for PKI-402 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; PI3K; mTOR Inhibitors; Signaling Pathways; Akt; mTOR Signaling; Inhibitors; Biochemicals; Biochemicals (A-Z)

Structure of PKI-402 biochemical

PKI-402 Biochemical – Cat# MBS848074

Product References and Citations for PKI-402 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/44187953#section=Top

Other Notes

Small volumes of PKI-402 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PKI-402 purchase

MBS848074 is a biochemical targeting PKI-402.
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