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Uprosertib

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848093

Uprosertib, also known as GSK2141795 and GSK795, is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Uprosertib, Biochemical
Full Product Name
Uprosertib
Product Synonym Names
Uprosertib; GSK-2141795; GSK2141795; GSK 2141795; GSK795; GSK795; GSK 795; N- ( (S)-1-amino-3- (3; 4-difluorophenyl) propan-2-yl)-5-chloro-4- (4-chloro-1-methyl-1H-pyrazol-5-yl) furan-2-carboxamide; N-[ (2S)-1-amino-3- (3; 4-difluorophenyl) propan-2-yl]-5-chloro-4- (4-chloro-2-methylpyrazol-3-yl) furan-2-carboxamide
Form/Format
Solid powder
Purity/Purification
>98%
Preparation and Storage
Store at -20 degree C
Protect from air and light
Shelf life: ~36 months
Molecular Weight
429.25
Solubility
DMSO
Molecular Formula
C??H??Cl?F?N?O?
CAS Number
1047634-65-0
PubChem CID
51042438
SMILES
CN1C (=C (C=N1)Cl)C2=C (OC (=C2)C (=O)NC (CC3=CC (=C (C=C3)F)F)CN)Cl
InChi
InChI=1S/C18H16Cl2F2N4O2/c1-26-16 (12 (19)8-24-26)11-6-15 (28-17 (11)20)18 (27)25-10 (7-23)4-9-2-3-13 (21)14 (22)5-9/h2-3,5-6,8,10H,4,7,23H2,1H3, (H,25,27)/t10-/m0/s1
InChi Key
AXTAPYRUEKNRBA-JTQLQIEISA-N

Product Categories/Family for Uprosertib biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; mTOR Inhibitors; Enzyme Inhibitors (A-Z); Signaling Pathways; PI3 K; Akt; mTOR Signaling; Inhibitors; Biochemicals; Biochemicals (A-Z)

Structure of Uprosertib biochemical

Uprosertib Biochemical – Cat# MBS848093

Product References and Citations for Uprosertib biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/51042438

Other Notes

Small volumes of Uprosertib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Uprosertib purchase

MBS848093 is a biochemical targeting Uprosertib.
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