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A-674563

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848094

A-674563 is a potent, orally available Akt1 inhibitor with an IC50 value of 11nM. Also displays activity against PKA and CDK2 with IC50 values of 16nM and 46nM respectively. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
A-674563, Biochemical
Full Product Name
A-674563
Product Synonym Names
A-674563; A674563; A 674563; (S)-1- ( (5- (3-methyl-1H-indazol-5-yl) pyridin-3-yl) oxy)-3-phenylpropan-2-amine; (2S)-1-[5- (3-methyl-2H-indazol-5-yl) pyridin-3-yl]oxy-3-phenylpropan-2-amine
Form/Format
Solid powder
Purity/Purification
>98%
Preparation and Storage
Store at -20 degree C
Protect from air and light
Shelf life: ~36 months
Molecular Weight
358.44
Solubility
DMSO
Molecular Formula
C??H??N?O
CAS Number
552325-73-2
MDL Number
MFCD18711680
PubChem CID
11314340
SMILES
CC1=C2C=C (C=CC2=NN1)C3=CC (=CN=C3)OCC (CC4=CC=CC=C4)N
InChi
InChI=1S/C22H22N4O/c1-15-21-11-17 (7-8-22 (21)26-25-15)18-10-20 (13-24-12-18)27-14-19 (23)9-16-5-3-2-4-6-16/h2-8,10-13,19H,9,14,23H2,1H3, (H,25,26)/t19-/m0/s1
InChi Key
BPNUQXPIQBZCMR-IBGZPJMESA-N

Product Categories/Family for A-674563 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; mTOR Inhibitors; Enzyme Inhibitors (A-Z); Signaling Pathways; PI3 K; Akt; mTOR Signaling; Inhibitors; Biochemicals; Biochemicals (A-Z)

Structure of A-674563 biochemical

A-674563 Biochemical – Cat# MBS848094

Product References and Citations for A-674563 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/11314340

Other Notes

Small volumes of A-674563 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for A-674563 purchase

MBS848094 is a biochemical targeting A-674563.
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