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Pyridoclax

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848116

Pyridoclax (MR-29072) is a potent Mcl-1 inhibitor (Kd = 25 nM).  Pyridoclax is able to disrupt BimL/Mcl-1 interaction in whole living cells. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Pyridoclax, Biochemical
Full Product Name
Pyridoclax
Product Synonym Names
(E)-3'-methyl-3''-styryl-3; 2':5'; 2'':5''; 3'''-quaterpyridine; MR29072
Form/Format
Crystalline solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C
Protect from air and light
Shelf life: ~36 months
Molecular Weight
426.51
Solubility
DMSO
Molecular Formula
C??H??N?
CAS Number
1651890-44-6
PubChem CID
92042827
SMILES
CC1=C (N=CC (=C1)C2=C (C=C (C=N2)C3=CN=CC=C3)C=CC4=CC=CC=C4)C5=CN=CC=C5
InChi
InChI=1S/C29H22N4/c1-21-15-27 (20-32-28 (21)25-10-6-14-31-18-25)29-23 (12-11-22-7-3-2-4-8-22)16-26 (19-33-29)24-9-5-13-30-17-24/h2-20H,1H3/b12-11+
InChi Key
WGGSYXQFYRWBEC-VAWYXSNFSA-N

Product Categories/Family for Pyridoclax biochemical

Bcl; 2 Inhibitors; Enzyme Inhibitors; Enzyme Inhibitors (A-Z); Biochemicals; Biochemicals (A-Z)

Structure of Pyridoclax biochemical

Pyridoclax Biochemical – Cat# MBS848116

Product References and Citations for Pyridoclax biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/92042827

Other Notes

Small volumes of Pyridoclax biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Pyridoclax purchase

MBS848116 is a biochemical targeting Pyridoclax.
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