Bosentan (4- (1)

Name: Bosentan (4- (1); MyBioSource
Brand: MyBioSource
SKU: MBS848155
Price: 205 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848155

Bosentan is an antagonist of the endothelin receptors type A (Ki = 6.5 nM) and type B (Ki = 340 nM). Inhibits ET-1 induced contraction of isolated rat aorta and sarafotoxin S6C-induced contraction of rat trachea in vitro. More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Bosentan, Biochemical

Full Product Name

Bosentan

Product Synonym Names

4- (1; 1-dimethylethyl)-N-[6- (2-hydroxyethoxy)-5- (2-methoxyphenoxy) [2; 2'-bipyrimidin]-4-yl]-benzenesulfonamide; Ro 47-0203

Form/Format

White solid

Purity/Purification

>=98% by HPLC

Preparation and Storage

Store at -20 degree C
Protect from air and light
Shelf life: ~36 months

Molecular Weight

551.61

Solubility

DMSO (>40 mg/ml) or EtOH (>20 mg/ml)

Molecular Formula

C??H??N?O?S

CAS Number

147536-97-8

PubChem CID

104865

SMILES

CC (C)(C)C1=CC=C (C=C1)S (=O)(=O)NC2=C (C (=NC (=N2)C3=NC=CC=N3)OCCO)OC4=CC=CC=C4OC

InChi

InChI=1S/C27H29N5O6S/c1-27 (2,3)18-10-12-19 (13-11-18)39 (34,35)32-23-22 (38-21-9-6-5-8-20 (21)36-4)26 (37-17-16-33)31-25 (30-23)24-28-14-7-15-29-24/h5-15,33H,16-17H2,1-4H3, (H,30,31,32)

InChi Key

GJPICJJJRGTNOD-UHFFFAOYSA-N

Product Categories/Family for Bosentan biochemical

Enzyme Inhibitors; Other Inhibitors; Enzyme Inhibitors (A-Z); Antiviral Agents; Biochemicals; Biochemicals (A-Z)

Product References and Citations for Bosentan biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/104865

Other Notes

Small volumes of Bosentan biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Bosentan purchase

MBS848155 is a biochemical targeting Bosentan.