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Pemetrexed

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848160

Pemetrexed is a high affinity dihydrofolate reductase (DHFR) inhibitor (Ki = 7 nM). Also inhibits thymidylate synthase, AICART and glycinamide ribonucleotide formyltransferase (Ki values are 109 nM, and 3.5 uM and 9.3 uM, respectively). Inhibits… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Pemetrexed, Biochemical
Full Product Name
Pemetrexed
Product Synonym Names
N-[4-[2- (2-Amino-4; 7-dihydro-4-oxo-3H-pyrrolo[2; 3-d]pyrimidin-5-yl) ethyl]benzoyl]-L-glutamic acid
Form/Format
White solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C
Protect from air and light
Shelf life: ~36 months
Molecular Weight
427.41
Solubility
DMSO (>40 mg/ml)
Molecular Formula
C??H??N?O?
CAS Number
137281-23-3
MDL Number
MFCD19105065
PubChem CID
446556
SMILES
C1=CC (=CC=C1CCC2=CNC3=C2C (=O)N=C (N3)N)C (=O)NC (CCC (=O)O)C (=O)O
InChi
InChI=1S/C20H21N5O6/c21-20-24-16-15 (18 (29)25-20)12 (9-22-16)6-3-10-1-4-11 (5-2-10)17 (28)23-13 (19 (30)31)7-8-14 (26)27/h1-2,4-5,9,13H,3,6-8H2, (H,23,28)(H,26,27)(H,30,31)(H4,21,22,24,25,29)/t13-/m0/s1
InChi Key
WBXPDJSOTKVWSJ-ZDUSSCGKSA-N

Product References and Citations for Pemetrexed biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/446556

Other Notes

Small volumes of Pemetrexed biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Pemetrexed purchase

MBS848160 is a biochemical targeting Pemetrexed.
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