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EML-425

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848180

EML-425 is a potent, reversible and non-competitive dual CBP and p300 inhibitor (IC50 values are 1.1 and 2.9 uM, respectively).  EML425 induced a marked and time-dependent reduction in the acetylation of lysine H4K5 and H3K9, a marked arrest in the G0/G1… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
EML-425, Biochemical
Full Product Name
EML-425
Product Synonym Names
5-[ (4-Hydroxy-2; 6-dimethylphenyl) methylene]-1; 3-bis (phenylmethyl)-2; 4; 6 (1H; 3H; 5H)-pyrimidinetrione
Form/Format
Yellow solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C
Protect from air and light
Shelf life: ~36 months
Molecular Weight
440.49
Solubility
DMSO (>40 mg/ml)
Molecular Formula
C??H??N?O?
CAS Number
1675821-32-5
SMILES
O=C1N (CC2=CC=CC=C2)C (/C (C (N1CC3=CC=CC=C3)=O)=C\C4=C (C)C=C (O)C=C4C)=O
InChi
InChI=1S/C27H24N2O4/c1-18-13-22 (30)14-19 (2)23 (18)15-24-25 (31)28 (16-20-9-5-3-6-10-20)27 (33)29 (26 (24)32)17-21-11-7-4-8-12-21/h3-15,30H,16-17H2,1-2H3
InChi Key
LUGQBJDYUPNAQQ-UHFFFAOYSA-N

Product Categories/Family for EML-425 biochemical

Enzyme Inhibitors; Histone Acetyltransferase (HAT) Inhibitors; Enzyme Inhibitors (A-Z); Biochemicals; Epigenetics; Epigenetic Modulators (A-Z); Biochemicals (A-Z)

Structure of EML-425 biochemical

EML-425 Biochemical – Cat# MBS848180

Other Notes

Small volumes of EML-425 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EML-425 purchase

MBS848180 is a biochemical targeting EML-425.
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