Ly-2784544 (Gandotinib)

Name: Ly-2784544 (Gandotinib); MyBioSource
Brand: MyBioSource
SKU: MBS848212
Price: 245 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848212

LY2784544 is a potent, selective and ATP-competitive JAK2 inhibitor (IC50 = 3 nM). effective in JAK2V617F, 8- and 20-fold selective versus JAK1 and JAK3. LY2784544 effectively inhibits JAK2V617F-driven signaling and cell proliferation in Ba/F3 cells… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

LY-2784544, Biochemical

Full Product Name

LY-2784544

Product Synonym Names

Gandotinib

Form/Format

Crystalline solid

Purity/Purification

>=98%

Preparation and Storage

Store at -20 degree C
Protect from air and light
Shelf life: ~36 months

Molecular Weight

469.94

Solubility

DMSO (>50 mg/ml)

Molecular Formula

C??H??ClFN?O

CAS Number

1229236-86-5

PubChem CID

46213929

SMILES

CC1=CC (=NN1)NC2=NN3C (=C (N=C3C (=C2)CN4CCOCC4)C)CC5=C (C=C (C=C5)Cl)F

InChi

InChI=1S/C23H25ClFN7O/c1-14-9-21 (29-28-14)27-22-11-17 (13-31-5-7-33-8-6-31)23-26-15 (2)20 (32 (23)30-22)10-16-3-4-18 (24)12-19 (16)25/h3-4,9,11-12H,5-8,10,13H2,1-2H3, (H2,27,28,29,30)

InChi Key

SQSZANZGUXWJEA-UHFFFAOYSA-N

Product Categories/Family for LY-2784544 biochemical

Signaling Pathways; JAK; Stat Signaling; JAK Inhibitors; Biochemicals; Biochemicals (A-Z)

Product References and Citations for LY-2784544 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/46213929

Other Notes

Small volumes of LY-2784544 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LY-2784544 purchase

MBS848212 is a biochemical targeting LY-2784544.