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PF-8380

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848225

PF-8380 is a potent and specific inhibitor of Autotaxin (ATX) (IC50 = 2.8 nM). Modulates lysophosphatidic acid (LPA) levels in vivo and in vitro by directly inhibiting autotaxin. Autotaxin (ATX) is a secreted enzyme having lysophospholipase D activity. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PF-8380, Biochemical
Full Product Name
PF-8380
Product Synonym Names
3; 5-dichlorobenzyl4- (3-oxo-3- (2-oxo-2; 3-dihydrobenzo[d]oxazol-6-yl) propyl) piperazine-1-carboxylate
Form/Format
Crystalline solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C
Protect from air and light
Shelf life: ~36 months
Molecular Weight
478.33
Solubility
DMSO (~20 mg/ml)
Molecular Formula
C??H??Cl?N?O?
CAS Number
1144035-53-9
PubChem CID
25265312
SMILES
C1CN (CCN1CCC (=O)C2=CC3=C (C=C2)NC (=O)O3)C (=O)OCC4=CC (=CC (=C4)Cl)Cl
InChi
InChI=1S/C22H21Cl2N3O5/c23-16-9-14 (10-17 (24)12-16)13-31-22 (30)27-7-5-26 (6-8-27)4-3-19 (28)15-1-2-18-20 (11-15)32-21 (29)25-18/h1-2,9-12H,3-8,13H2, (H,25,29)
InChi Key
JMSUDQYHPSNBSN-UHFFFAOYSA-N

Product Categories/Family for PF-8380 biochemical

Enzyme Inhibitors; Other Inhibitors; Enzyme Inhibitors (A-Z); Antiviral Agents; Biochemicals; Biochemicals (A-Z)

Structure of PF-8380 biochemical

Pf-8380 Biochemical – Cat# MBS848225

Product References and Citations for PF-8380 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/25265312

Other Notes

Small volumes of PF-8380 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PF-8380 purchase

MBS848225 is a biochemical targeting PF-8380.
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