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Serabelisib

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848228

Serabelisib is a potent inhibitor of phosphoinositide 3-kinase alpha (PI3Kalpha) that is selective for p110alpha in vitro  (IC50 = 15 nM for PI3Kalpha vs. >1 uM for other isoforms, as well as for mTOR) . MLN1117 inhibits AKT phosphorylation and growth… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Serabelisib, Biochemical
Full Product Name
Serabelisib
Product Synonym Names
[6- (2-amino-5-benzoxazolyl) imidazo[1; 2-a]pyridin-3-yl]-4-morpholinyl-methanone; MLN1117; INK1117; TAK-117)
Form/Format
Brown solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C
Protect from air and light
Shelf life: ~36 months
Molecular Weight
363.34
Solubility
DMSO (~1 mg/ml)
Molecular Formula
C??H??N?O?
CAS Number
1268454-23-4
PubChem CID
70798655
SMILES
C1COCCN1C (=O)C2=CN=C3N2C=C (C=C3)C4=CC5=C (C=C4)OC (=N5)N
InChi
InChI=1S/C19H17N5O3/c20-19-22-14-
InChi Key
BLGWHBSBBJNKJO-UHFFFAOYSA-N

Product Categories/Family for Serabelisib biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; PI 3; Kinase Inhibitors; Enzyme Inhibitors (A-Z); Biochemicals; Biochemicals (A-Z)

Structure of Serabelisib biochemical

Serabelisib Biochemical – Cat# MBS848228

Product References and Citations for Serabelisib biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/70798655

Other Notes

Small volumes of Serabelisib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Serabelisib purchase

MBS848228 is a biochemical targeting Serabelisib.
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