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Hesperadin

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848238

Hesperadin is a potent, ATP-competitive inhibitor of Aurora B kinase (IC50 = 250 nM). Hesperadin inhibits Aurora B kinase by phosphorylation of histone H3. Also acts as a broad-spectrum influenza antiviral agent. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Hesperadin, Biochemical
Full Product Name
Hesperadin
Product Synonym Names
N-[ (3Z)-2-oxo-3-[phenyl-[4- (piperidin-1-ylmethyl) anilino]methylidene]-1H-indol-5-yl]ethanesulfonamide
Form/Format
Crystalline solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C
Protect from air and light
Shelf life: ~36 months
Molecular Weight
516.65
Solubility
DMSO (>25 mg/ml)
Molecular Formula
C??H??N?O?S
CAS Number
422513-13-1
PubChem CID
10142586
SMILES
CCS (=O)(=O)NC1=CC2=C (C=C1)NC (=O)C2=C (C3=CC=CC=C3)NC4=CC=C (C=C4)CN5CCCCC5
InChi
InChI=1S/C29H32N4O3S/c1-2-37 (35,36)32-24-15-16-26-25 (19-24)27 (29 (34)31-26)28 (22-9-5-3-6-10-22)30-23-13-11-21 (12-14-23)20-33-17-7-4-8-18-33/h3,5-6,9-16,19,30,32H,2,4,7-8,17-18,20H2,1H3, (H,31,34)/b28-27-
InChi Key
GLDSKRNGVVYJAB-DQSJHHFOSA-N

Product Categories/Family for Hesperadin biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; Aurora Kinase Inhibitors; Enzyme Inhibitors (A-Z); Biochemicals (A-Z)

Structure of Hesperadin biochemical

Hesperadin Biochemical – Cat# MBS848238

Product References and Citations for Hesperadin biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/10142586

Other Notes

Small volumes of Hesperadin biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Hesperadin purchase

MBS848238 is a biochemical targeting Hesperadin.
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