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MLN-8054

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848241

MLN-8054 is a potent and selective inhibitor of Aurora kinase A (IC50 = 4 nM). Displays 40-fold selectivity for Aurora A over Aurora B. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
MLN-8054, Biochemical
Full Product Name
MLN-8054
Product Synonym Names
4-[[9-chloro-7- (2; 6-difluorophenyl)-5H-pyrimido[5; 4-d][2]benzazepin-2-yl]amino]benzoic acid
Form/Format
Crystalline solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C
Protect from air and light
Shelf life: ~36 months
Molecular Weight
476.86
Solubility
DMSO (>35 mg/ml)
Molecular Formula
C??H??ClF?N?O?
CAS Number
869363-13-3
PubChem CID
11712649
SMILES
C1C2=CN=C (N=C2C3=C (C=C (C=C3)Cl)C (=N1)C4=C (C=CC=C4F)F)NC5=CC=C (C=C5)C (=O)O
InChi
InChI=1S/C25H15ClF2N4O2/c26-15-6-9-17-18 (10-15)23 (21-19 (27)2-1-3-20 (21)28)29-11-14-12-30-25 (32-22 (14)17)31-16-7-4-13 (5-8-16)24 (33)34/h1-10,12H,11H2, (H,33,34)(H,30,31,32)
InChi Key
HHFBDROWDBDFBR-UHFFFAOYSA-N

Product Categories/Family for MLN-8054 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; Aurora Kinase Inhibitors; Enzyme Inhibitors (A-Z); Biochemicals (A-Z)

Structure of MLN-8054 biochemical

MLN-8054 Biochemical – Cat# MBS848241

Product References and Citations for MLN-8054 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/11712649

Other Notes

Small volumes of MLN-8054 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MLN-8054 purchase

MBS848241 is a biochemical targeting MLN-8054.
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