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IPI-549

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848266

IPI-549 is a potent and selective PI3Kgamma Inhibitor (IC50 of 16 nM). It displays no significant inhibition for a panel of 468 mutant and non-mutant protein and lipid kinases (including Class II PI3K isoforms) at 1 uM. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
IPI-549, Biochemical
Full Product Name
IPI-549
Product Synonym Names
2-amino-N-[1-[8-[2- (1-methylpyrazol-4-yl) ethynyl]-1-oxo-2-phenylisoquinolin-3-yl]ethyl]pyrazolo[1; 5-a]pyrimidine-3-carboxamide
Form/Format
Crystalline solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C
Protect from air and light
Shelf life: ~36 months
Molecular Weight
528.56
Solubility
DMSO (~15 mg/ml)
Molecular Formula
C??H??N?O?
CAS Number
1693758-51-8
PubChem CID
118004470
SMILES
CC (C1=CC2=CC=CC (=C2C (=O)N1C3=CC=CC=C3)C#CC4=CN (N=C4)C)NC (=O)C5=C6N=CC=CN6N=C5N
InChi
InChI=1S/C30H24N8O2/c1-19 (34-29 (39)26-27 (31)35-37-15-7-14-32-28 (26)37)24-16-22-9-6-8-21 (13-12-20-17-33-36 (2)18-20)25 (22)30 (40)38 (24)23-10-4-3-5-11-23/h3-11,14-19H,1-2H3, (H2,31,35)(H,34,39)
InChi Key
XUMALORDVCFWKV-UHFFFAOYSA-N

Structure of IPI-549 biochemical

IPI-549 Biochemical – Cat# MBS848266

Product References and Citations for IPI-549 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/118004470

Other Notes

Small volumes of IPI-549 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IPI-549 purchase

MBS848266 is a biochemical targeting IPI-549.
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