• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Brigatinib analog

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848318

Brigantinib alalog is an analog of Brigatinib (AP26113) , a phosphine oxide-containing ALK inhibitor. It potently inhibits ALK (IC50 = 0.07 nM) over IGF-1R and InsR (IC50s = 3.2 and 100 nM, respectively. More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Product Name
Brigatinib analog, Biochemical
Full Product Name
Brigatinib analog
Product Synonym Names
(2- ( (5-chloro-2- ( (4- (4- (dimethylamino) piperidin-1-yl)-2-methoxyphenyl) amino) pyrimidin-4-yl) amino) phenyl) dimethylphosphine oxide; AP-26113 analog; ALK-IN-1
Form/Format
White to off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C
Protect from air and light
Shelf life: ~36 months
Molecular Weight
529.01
Solubility
DMSO
Molecular Formula
C??H??ClN?O?P 
CAS Number
1197958-12-5
PubChem CID
57390074
SMILES
CN (C)C1CCN (CC1)C2=CC (=C (C=C2)NC3=NC=C (C (=N3)NC4=CC=CC=C4P (=O)(C)C)Cl)OC
InChi
InChI=1S/C26H34ClN6O2P/c1-32 (2)18-12-14-33 (15-13-18)19-10-11-21 (23 (16-19)35-3)30-26-28-17-20 (27)25 (31-26)29-22-8-6-7-9-24 (22)36 (4,5)34/h6-11,16-18H,12-15H2,1-5H3, (H2,28,29,30,31)
InChi Key
OVDSPTSBIQCAIN-UHFFFAOYSA-N

Product Categories/Family for Brigatinib analog biochemical

Biochemicals; Enzyme Inhibitors; Protein Kinase Inhibitors; ALK (Anaplastic Lymphoma Kinase) Inhibitors; Enzyme Inhibitors (A-Z); Protein Kinase Inhibitors (A-Z); Biochemicals (A-Z)

Structure of Brigatinib analog biochemical

Brigatinib Analog Biochemical – Cat# MBS848318

Product References and Citations for Brigatinib analog biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/57390074

Other Notes

Small volumes of Brigatinib analog biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Brigatinib analog purchase

MBS848318 is a biochemical targeting Brigatinib analog.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000