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Belizatinib (TSR-011)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848321

Belizatinib (TSR-011) is a potent inhibitor of both the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) and the tropomyosin-related kinases (TRK) TRKA, TRKB, and TRKC, with potential antineoplastic activity. The inhibition leads to disruption of… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Belizatinib, Biochemical
Full Product Name
Belizatinib (TSR-011)
Product Synonym Names
4-fluoro-N- (6- ( (4- (2-hydroxypropan-2-yl) piperidin-1-yl) methyl)-1- ( (1s; 4s)-4- (isopropylcarbamoyl) cyclohexyl)-1H-benzo[d]imidazol-2-yl) benzamide; TSR011
Form/Format
Crystalline solid
Purity/Purification
>=98%
Preparation and Storage
Store at -20 degree C
Protect from air and light
Shelf life: ~36 months
Molecular Weight
577.75
Solubility
DMSO
Molecular Formula
C??H??FN?O?
CAS Number
1357920-84-3
PubChem CID
57345941
SMILES
CC (C)NC (=O)C1CCC (CC1)N2C3=C (C=CC (=C3)CN4CCC (CC4)C (C)(C)O)N=C2NC (=O)C5=CC=C (C=C5)F
InChi
InChI=1S/C33H44FN5O3/c1-21 (2)35-30 (40)24-8-12-27 (13-9-24)39-29-19-22 (20-38-17-15-25 (16-18-38)33 (3,4)42)5-14-28 (29)36-32 (39)37-31 (41)23-6-10-26 (34)11-7-23/h5-7,10-11,14,19,21,24-25,27,42H,8-9,12-13,15-18,20H2,1-4H3, (H,35,40)(H,36,37,41)
InChi Key
WSTUJEXAPHIEIM-UHFFFAOYSA-N

Product References and Citations for Belizatinib biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/57345941

Other Notes

Small volumes of Belizatinib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Belizatinib purchase

MBS848321 is a biochemical targeting Belizatinib. Also known as Belizatinib (TSR-011).
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