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Plinabulin ((3Z)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848342

Plinabulin (NPI-2358) is a vascular disrupting agent (VDA). Plinabulin binds to the colchicine binding site of beta-tubulin preventing polymerization and disrupting the cytoplasmic microtubule network. It is also an antineoplastic agent that activates an… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Plinabulin, Biochemical
Full Product Name
Plinabulin
Product Synonym Names
(3Z; 6Z)-3-benzylidene-6-[ (5-tert-butyl-1H-imidazol-4-yl) methylidene]piperazine-2; 5-dione; NPI-2358
Form/Format
Yellow solid
Purity/Purification
>=98%
Preparation and Storage
Store at -20 degree C
Protect from air and light
Shelf life: ~36 months
Molecular Weight
336.39
Solubility
DMSO (~5 mg/ml)
Molecular Formula
C??H??N?O? 
CAS Number
714272-27-2 
PubChem CID
949641
SMILES
CC (C)(C)C1=C (N=CN1)C=C2C (=O)NC (=CC3=CC=CC=C3)C (=O)N2
InChi
InChI=1S/C19H20N4O2/c1-19 (2,3)16-13 (20-11-21-16)10-15-18 (25)22-14 (17 (24)23-15)9-12-7-5-4-6-8-12/h4-11H,1-3H3, (H,20,21)(H,22,25)(H,23,24)/b14-9-,15-10-
InChi Key
NRCMCRRFYFGFX-TYPNBTCFSA-N

Product References and Citations for Plinabulin biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/9949641

Other Notes

Small volumes of Plinabulin biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Plinabulin purchase

MBS848342 is a biochemical targeting Plinabulin.
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