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PF-04217903

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848354

PF-04217903 is a novel ATP-competitive small-molecule inhibitor of c-Met kinase. PF-04217903 displays more than 1,000-fold selectivity for c-Met compared with more than 150 kinases. PF-04217903 inhibits tumor cell proliferation, survival, migration/invasion… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PF-04217903, Biochemical
Full Product Name
PF-04217903
Product Synonym Names
4-[1- (6-Quinolinylmethyl)-1H-1; 2; 3-triazolo[4; 5-b]pyrazin-6-yl]-1H-pyrazole-1-ethanol
Form/Format
White to off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C
Protect from air and light
Shelf life: ~36 months
Molecular Weight
372.4
Solubility
DMSO
Molecular Formula
C??H??N?O
CAS Number
956905-27-4
PubChem CID
7754438
SMILES
C1=CC2=C (C=CC (=C2)CN3C4=NC (=CN=C4N=N3)C5=CN (N=C5)CCO)N=C1
InChi
InChI=1S/C19H16N8O/c28-7-6-26-12-15 (9-22-26)17-10-21-18-19 (23-17)27 (25-24-18)11-13-3-4-16-14 (8-13)2-1-5-20-16/h1-5,8-10,12,28H,6-7,11H2
InChi Key
PDMUGYOXRHVNMO-UHFFFAOYSA-N

Product Categories/Family for PF-04217903 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Tyrosine Kinase Inhibitors; Enzyme Inhibitors (A-Z); Signaling Pathways; EGFR Signaling; EGFR Inhibitors; Cancer Research; Oncogenic Signaling Pathway; Biochemicals; Biochemicals (A-Z)

Structure of PF-04217903 biochemical

Pf-04217903 Biochemical – Cat# MBS848354

Product References and Citations for PF-04217903 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/17754438

Other Notes

Small volumes of PF-04217903 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PF-04217903 purchase

MBS848354 is a biochemical targeting PF-04217903.
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