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AZD-5438

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848363

AZD-5438 is a potent inhibitor of cyclin-dependent kinases (CDKs) (IC50 values are 16, 6 and 20 nM for CDK1, 2, and 9, respectively). Displays antiproliferative activity in human tumor cell lines. It is less potent to CDK5/6 and also inhibits GSK3beta. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
AZD-5438, Biochemical
Full Product Name
AZD-5438
Product Synonym Names
4- (1-isopropyl-2-methyl-1H-imidazol-5-yl)-N- (4- (methylsulfonyl) phenyl) pyrimidin-2-amine
Form/Format
Off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C
Protect from air and light
Shelf life: ~36 months
Molecular Weight
371.46
Solubility
DMSO (>30 mg/ml)
Molecular Formula
C??H??N?OS
CAS Number
602306-29-6
PubChem CID
16747683
SMILES
CC1=NC=C (N1C (C)C)C2=NC (=NC=C2)NC3=CC=C (C=C3)S (=O)(=O)C
InChi
InChI=1S/C18H21N5O2S/c1-12 (2)23-13 (3)20-11-17 (23)16-9-10-19-18 (22-16)21-14-5-7-15 (8-6-14)26 (4,24)25/h5-12H,1-4H3, (H,19,21,22)
InChi Key
WJRRGYBTGDJBFX-UHFFFAOYSA-N

Product Categories/Family for AZD-5438 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; CDK Inhibitors; Enzyme Inhibitors (A-Z); Biochemicals; Biochemicals (A-Z)

Structure of AZD-5438 biochemical

AZD-5438 Biochemical – Cat# MBS848363

Product References and Citations for AZD-5438 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/16747683

Other Notes

Small volumes of AZD-5438 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AZD-5438 purchase

MBS848363 is a biochemical targeting AZD-5438.
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