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CB-1158

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848507

CB-1158 (INCB001158) is a potent, and selective inhibitor of human arginase I (IC50 = 98 nM), an immune-mediated anti-tumor agent. Displays potential for anti-tumor activity in renal cell cancer, breast cancer, non-small cell lung cancer, acute myeloid… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
CB-1158, Biochemical
Full Product Name
CB-1158
Product Synonym Names
2-Amino-6-borono-2- (1- (2; 4-dichlorobenzyl) piperidin-4-yl) hexanoic acid; INCB001158
Form/Format
White to off-white solid
Purity/Purification
>=97% by HPLC
Preparation and Storage
Store at -20 degree C
Protect from air and light
Shelf life: ~36 months
Molecular Weight
287.12
Solubility
DMSO
Molecular Formula
C??H??BN?O?
CAS Number
2095732-06-0
SMILES
ClC1=CC (Cl)=CC=C1CN2CCC (C (N)(CCCCB (O)O)C (O)=O)CC2
InChi
InChI=1S/C18H27BCl2N2O4/c20-15-4-3-13 (16 (21)11-15)12-23-9-5-14 (6-10-23)18 (22,17 (24)25)7-1-2-8-19 (26)27/h3-4,11,14,26-27H,1-2,5-10,12,22H2, (H,24,25)
InChi Key
ISYBHIALKUAHGV-UHFFFAOYSA-N

Product Categories/Family for CB-1158 biochemical

Biochemicals; Enzyme Inhibitors; Arginase Inhibitors; Enzyme Inhibitors (A-Z); Biochemicals (A-Z)

Structure of CB-1158 biochemical

Cb-1158 Biochemical – Cat# MBS848507

Other Notes

Small volumes of CB-1158 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CB-1158 purchase

MBS848507 is a biochemical targeting CB-1158.
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