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Autophinib

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848538

Autophinib is a potent autophagy inhibitor. It inhibits autophagy induced by starvation or rapamycin by targeting the lipid kinase VPS34 with IC50s of 90, 40 and 19 nM, respectively. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Autophinib, Biochemical
Full Product Name
Autophinib
Product Synonym Names
6-Chloro-N- (5-methyl-1H-pyrazol-3-yl)-2- (4-nitrophenoxy)-pyrimidinamine
Form/Format
White solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C
Protect from air and light
Shelf life: ~36 months
Molecular Weight
346.73
Solubility
DMSO (>6 mg/ml)
Molecular Formula
C??H??ClN?O?
CAS Number
1644443-47-9
PubChem CID
129626605
SMILES
CC1=CC (=NN1)NC2=CC (=NC (=N2)OC3=CC=C (C=C3)[N+] (=O)[O-])Cl
InChi
InChI=1S/C14H11ClN6O3/c1-8-6-13 (20-19-8)17-12-7-11 (15)16-14 (18-12)24-10-4-2-9 (3-5-10)21 (22)23/h2-7H,1H3, (H2,16,17,18,19,20)
InChi Key
CEUMAXLRGBKFQP-UHFFFAOYSA-N

Product Categories/Family for Autophinib biochemical

Apoptosis & Related Products;  Autophagy; Autophagy Inhibitors; Biochemicals; Biochemicals (A-Z)

Structure of Autophinib biochemical

Autophinib Biochemical – Cat# MBS848538

Product References and Citations for Autophinib biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/129626605

Other Notes

Small volumes of Autophinib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Autophinib purchase

MBS848538 is a biochemical targeting Autophinib.
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