EI1 (6-cyano-N-[ (1)

Name: EI1 (6-cyano-N-[ (1); MyBioSource
Brand: MyBioSource
SKU: MBS848548
Price: 245 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848548

EI1 is a potent EZH2 inhibitor that has activity against both wild-type and Y641F mutant EZH2 (IC50s = 15 and 13 nM, respectively) . It displays 90-fold selectivity for EZH2 over EZH1 and >10,000-fold selectivity over other lysine methyltransferases. EI1… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

EI1, Biochemical

Full Product Name

EI1

Product Synonym Names

6-cyano-N-[ (1; 2-dihydro-4; 6-dimethyl-2-oxo-3-pyridinyl) methyl]-1- (1-ethylpropyl)-1H-indole-4-carboxamide

Form/Format

White solid

Purity/Purification

>=98% by HPLC

Preparation and Storage

Store at -20 degree C
Protect from air and light
Shelf life: ~36 months

Molecular Weight

390.5

Solubility

DMSO (~2 mg/ml)

Molecular Formula

C??H??N?O?

CAS Number

1418308-27-6

PubChem CID

72199293

SMILES

CCC (CC)N1C=CC2=C (C=C (C=C21)C#N)C (=O)NCC3=C (C=C (NC3=O)C)C

InChi

InChI=1S/C23H26N4O2/c1-5-17 (6-2)27-8-7-18-19 (10-16 (12-24)11-21 (18)27)22 (28)25-13-20-14 (3)9-15 (4)26-23 (20)29/h7-11,17H,5-6,13H2,1-4H3, (H,25,28)(H,26,29)

InChi Key

PFHDWRIVDDIFRP-UHFFFAOYSA-N

Product Categories/Family for EI1 biochemical

Epigenetics; Epigenetic Modulators (A-Z); Biochemicals; Biochemicals (A-Z)

Product References and Citations for EI1 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/72199293

Other Notes

Small volumes of EI1 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EI1 purchase

MBS848548 is a biochemical targeting EI1.