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PF-670462

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848549

PF-670462 is a potent and selective casein kinase 1epsilon  (CK1epsilon) and CK1delta inhibitor (IC50 values are 7.7 and 14 nM respectively) that displays > 30-fold selectivity over 42 other kinases. Inhibits PER protein nuclear translocation (EC50 = 290… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PF-670462, Biochemical
Full Product Name
PF-670462
Product Synonym Names
4-[1-Cyclohexyl-4- (4-fluorophenyl)-1H-imidazol-5-yl]-2-pyrimidinamine dihydrochloride
Form/Format
Off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C
Protect from air and light
Shelf life: ~36 months
Molecular Weight
410.32
Solubility
DMSO (>35 mg/ml) or H2O (>35 mg/ml)
Molecular Formula
C??H??FN?-2HCl
CAS Number
950912-80-8
PubChem CID
51049607
SMILES
C1CCC (CC1)N2C=NC (=C2C3=NC (=NC=C3)N)C4=CC=C (C=C4)F.Cl.Cl
InChi
InChI=1S/C19H20FN5.2ClH/c20-14-8-6-13 (7-9-14)17-18 (16-10-11-22-19 (21)24-16)25 (12-23-17)15-4-2-1-3-5-15;;/h6-12,15H,1-5H2, (H2,21,22,24);2*1H
InChi Key
PSNKGVAXBSAHCH-UHFFFAOYSA-N

Product Categories/Family for PF-670462 biochemical

Biochemicals; Enzyme Inhibitors; Protein Kinase Inhibitors; Casein Kinase Inhibitors; Enzyme Inhibitors (A-Z); Biochemicals (A-Z)

Structure of PF-670462 biochemical

Pf-670462 Biochemical – Cat# MBS848549

Product References and Citations for PF-670462 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/51049607#section=Top

Other Notes

Small volumes of PF-670462 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PF-670462 purchase

MBS848549 is a biochemical targeting PF-670462.
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