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LW6

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848555

LW6 is a potent HIF-1 inhibitor (IC50 = 4.4 uM). It promotes proteasomal degradation of HIF-1alpha via upregulation of von-Hippel-Landau (VHL) without affecting the activity of prolyl hydroxylase (PHD) . More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
LW6, Biochemical
Full Product Name
LW6
Product Synonym Names
4-hydroxy-3-[[2- (4-tricyclo[3.3.1.13; 7]dec-1-ylphenoxy) acetyl]amino]-benzoic acid; methyl ester; CAY10585
Form/Format
Off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C
Protect from air and light
Shelf life: ~36 months
Molecular Weight
435.51
Solubility
DMSO (~10 mg/ml)
Molecular Formula
C??H??NO?
CAS Number
934593-90-5
PubChem CID
16124726
SMILES
COC (=O)C1=CC (=C (C=C1)O)NC (=O)COC2=CC=C (C=C2)C34CC5CC (C3)CC (C5)C4
InChi
InChI=1S/C26H29NO5/c1-31-25 (30)19-2-7-23 (28)22 (11-19)27-24 (29)15-32-21-5-3-20 (4-6-21)26-12-16-8-17 (13-26)10-18 (9-16)14-26/h2-7,11,16-18,28H,8-10,12-15H2,1H3, (H,27,29)
InChi Key
BJRPPNOJYFZSLY-UHFFFAOYSA-N

Product Categories/Family for LW6 biochemical

Biochemicals; Enzyme Inhibitors; HIF Inhibitors; Enzyme Inhibitors (A-Z); Biochemicals (A-Z)

Structure of LW6 biochemical

LW6 Biochemical – Cat# MBS848555

Product References and Citations for LW6 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/16124726

Other Notes

Small volumes of LW6 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LW6 purchase

MBS848555 is a biochemical targeting LW6.
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