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Nazartinib

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848566

Nazartinib is a potent, irreversible, third-generation, mutant-selective epidermal growth factor receptor (EGFR) inhibitor, with potential antineoplastic activity. It covalently binds to and inhibits the activity of mutant forms of EGFR, including the T790M… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Nazartinib, Biochemical
Full Product Name
Nazartinib
Product Synonym Names
(R; E)-N- (7-chloro-1- (1- (4- (dimethylamino) but-2-enoyl) azepan-3-yl)-1H-benzo[d]imidazol-2-yl)-2-methylisonicotinamide; EGF816; NSV816
Form/Format
White to off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C
Protect from air and light
Shelf life: ~36 months
Molecular Weight
495.02
Solubility
DMSO
Molecular Formula
C??H??lN?O?
CAS Number
1508250-71-2
PubChem CID
72703790
SMILES
CC1=NC=CC (=C1)C (=O)NC2=NC3=C (N2C4CCCCN (C4)C (=O)C=CCN (C)C)C (=CC=C3)Cl
InChi
InChI=1S/C26H31ClN6O2/c1-18-16-19 (12-13-28-18)25 (35)30-26-29-22-10-6-9-21 (27)24 (22)33 (26)20-8-4-5-15-32 (17-20)23 (34)11-7-14-31 (2)3/h6-7,9-13,16,20H,4-5,8,14-15,17H2,1-3H3, (H,29,30,35)/b11-7+/t20-/m1/s1
InChi Key
IOMMMLWIABWRKL-WUTDNEBXSA-N

Product Categories/Family for Nazartinib biochemical

Biochemicals; Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Tyrosine Kinase Inhibitors; Enzyme Inhibitors (A-Z); Biochemicals (A-Z)

Structure of Nazartinib biochemical

Nazartinib Biochemical – Cat# MBS848566

Product References and Citations for Nazartinib biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/72703790

Other Notes

Small volumes of Nazartinib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Nazartinib purchase

MBS848566 is a biochemical targeting Nazartinib.
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