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BAY 11-7085

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848606

An irreversible inhibitor of IkappaBalpha phosphorylation, preventing activation of NF-kappaB by cytokines and lipopolysaccharide (IC50 = 10 uM). It prevents gene expression that is regulated through the classical pathway of NF-kappaB activation and thus… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
BAY 11-7085, Biochemical
Full Product Name
BAY 11-7085
Product Synonym Names
(E)-3- (4-t-Butylphenylsulfonyl)-2-propenenitrile; 3-[[4- (1; 1-dimethylethyl) phenyl]sulfonyl]-2E-propenenitrile
Form/Format
White solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months
Molecular Weight
249.33
Solubility
>20 mg/ml (EtOH),>20 mg/ml (DMSO)
Molecular Formula
C??H??NO?S
CAS Number
196309-76-9
MDL Number
MFCD01862602
PubChem CID
5353432
SMILES
CC (C)(C)C1=CC=C (C=C1)S (=O)(=O)C=CC#N
InChi
InChI=1S/C13H15NO2S/c1-13 (2,3)11-5-7-12 (8-6-11)17 (15,16)10-4-9-14/h4-8,10H,1-3H3/b10-4+
InChi Key
VHKZGNPOHPFPER-ONNFQVAWSA-N

Product Categories/Family for BAY 11-7085 biochemical

Enzyme Inhibitors; Enzyme Inhibitors (A-Z); Enzyme Inhibitors; NF; KB Pathway Inhibitors; Biochemicals; Biochemicals (A-Z)

Structure of BAY 11-7085 biochemical

BAY 11-7085 Biochemical – Cat# MBS848606

Product References and Citations for BAY 11-7085 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/5353432

Other Notes

Small volumes of BAY 11-7085 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BAY 11-7085 purchase

MBS848606 is a biochemical targeting BAY 11-7085.
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