Ledipasvir (GS-5885)

Name: Ledipasvir (GS-5885); MyBioSource
Brand: MyBioSource
SKU: MBS848614
Price: 220 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848614

Ledipasvir is a potent inhibitor of the hepatitis C virus (HCV) non-structural protein 5A (NS5A) replication complex, with potential activity against HCV. Upon oral administration and after intracellular uptake, ledipasvir binds to and blocks the activity of… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Ledipasvir, Biochemical

Full Product Name

Ledipasvir

Product Synonym Names

GS-5885; Harvoni; Methyl N-[ (2S)-1-[ (6S)-6-[5-[9; 9-Difluoro-7-[2-[ (1S; 2S; 4R)-3-[ (2S)-2- (methoxycarbonylamino)-3-methylbutanoyl]-3-azabicyclo[2.2.1]heptan-2-yl]-3H-benzimidazol-5-yl]fluoren-2-yl]-1H-imidazol-2-yl]-5-azaspiro[2.4]heptan-5-yl]-3-methyl-1-oxobutan-2-yl]carbamate; GS5885

Form/Format

Off-white solid

Purity/Purification

>=98% by HPLC

Preparation and Storage

Store at -20 degree C
Shelf life: ~36 months

Molecular Weight

889

Solubility

>10 mg/ml (DMSO)

Molecular Formula

C??H??F?N?O?

CAS Number

1256388-51-8

PubChem CID

67505836

SMILES

CC (C)C (C (=O)N1CC2 (CC2)CC1C3=NC=C (N3)C4=CC5=C (C=C4)C6=C (C5 (F)F)C=C (C=C6)C7=CC8=C (C=C7)N=C (N8)C9C1CCC (C1)N9C (=O)C (C (C)C)NC (=O)OC)NC (=O)OC

InChi

InChI=1S/C49H54F2N8O6/c1-24 (2)39 (56-46 (62)64-5)44 (60)58-23-48 (15-16-48)21-38 (58)42-52-22-37 (55-42)28-9-13-32-31-12-8-26 (18-33 (31)49 (50,51)34 (32)19-28)27-10-14-35-36 (20-27)54-43 (53-35)41-29-7-11-30 (17-29)59 (41)45 (61)40 (25 (3)4)57-47 (63)65-6/h8-10,12-14,18-20,22,24-25,29-30,38-41H,7,11,15-17,21,23H2,1-6H3, (H,52,55)(H,53,54)(H,56,62)(H,57,63)/t29-,30+,38-,39-,40-,41-/m0/s1

InChi Key

VRTWBAAJJOHBQU-KMWAZVGDSA-N

Product Categories/Family for Ledipasvir biochemical

Biochemicals; Biochemicals (A-Z); Antiviral Agents

Product References and Citations for Ledipasvir biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/Ledipasvir#section=Top

Other Notes

Small volumes of Ledipasvir biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Ledipasvir purchase

MBS848614 is a biochemical targeting Ledipasvir.