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TAS-120

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848630

TAS-120 is a novel, potent and highly selective FGFR inhibitor that irreversibly inhibits all four FGFR subtypes at nanomolar concentrations. It blocks the phosphorylation of FGFRs and impedes downstream signaling pathways in cells. TAS-120 prevents the… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
TAS-120, Biochemical
Full Product Name
TAS-120
Product Synonym Names
1-[ (3S)-3-[4-amino-3-[2- (3; 5-dimethoxyphenyl) ethynyl]-1H-pyrazolo[3; 4-d]pyrimidin-1-yl]-1-pyrrolidinyl]-2-propen-1-one
Form/Format
Crystalline solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months
Molecular Weight
418.5
Solubility
>25 mg/ml (DMSO)
Molecular Formula
C??H??N?O?
CAS Number
1448169-71-8
PubChem CID
71621331
SMILES
COC1=CC (=CC (=C1)C#CC2=NN (C3=C2C (=NC=N3)N)C4CCN (C4)C (=O)C=C)OC
InChi
InChI=1S/C22H22N6O3/c1-4-19 (29)27-8-7-15 (12-27)28-22-20 (21 (23)24-13-25-22)18 (26-28)6-5-14-9-16 (30-2)11-17 (10-14)31-3/h4,9-11,13,15H,1,7-8,12H2,2-3H3, (H2,23,24,25)/t15-/m0/s1
InChi Key
KEIPNCCJPRMIAX-HNNXBMFYSA-N

Product Categories/Family for TAS-120 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Kinase Inhibitors  (A-Z); Biochemicals; Biochemicals (A-Z); Protein Tyrosine Kinase Inhibitors; Enzyme Inhibitors (A-Z)

Structure of TAS-120 biochemical

TAS-120 Biochemical – Cat# MBS848630

Product References and Citations for TAS-120 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/71621331

Other Notes

Small volumes of TAS-120 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TAS-120 purchase

MBS848630 is a biochemical targeting TAS-120.
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