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Alvimopan (ADL 8-2698)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848747

Alvimopan is a peripherally acting u-opioid receptor antagonist (Ki = 0.47 nM) that is selective over the kappa- and delta-opioid receptors (Ki's = 100 nM and 12 nM, respectively). It is used to avoid postoperative ileus following small or large bowel… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Alvimopan, Biochemical
Full Product Name
Alvimopan
Product Synonym Names
ADL 8-2698; N-[ (2S)-2-[[ (3R; 4R)-4- (3-hydroxyphenyl)-3; 4-dimethyl-1-piperidinyl]methyl]-1-oxo-3-phenylpropyl]-glycine; LY246736
Form/Format
Crystalline solid
Purity/Purification
>=98%
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months
Molecular Weight
424.5
Solubility
~20 mg/ml in DMSO
Molecular Formula
C??H??N?O?
CAS Number
156053-89-3
PubChem CID
5488548
SMILES
CC1CN (CCC1 (C)C2=CC (=CC=C2)O)CC (CC3=CC=CC=C3)C (=O)NCC (=O)O
InChi
InChI=1S/C25H32N2O4/c1-18-16-27 (12-11-25 (18,2)21-9-6-10-22 (28)14-21)17-20 (24 (31)26-15-23 (29)30)13-19-7-4-3-5-8-19/h3-10,14,18,20,28H,11-13,15-17H2,1-2H3, (H,26,31)(H,29,30)/t18-,20-,25+/m0/s1
InChi Key
UPNUIXSCZBYVBB-JVFUWBCBSA-N

Product References and Citations for Alvimopan biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/5488548

Other Notes

Small volumes of Alvimopan biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Alvimopan purchase

MBS848747 is a biochemical targeting Alvimopan.
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