CCT-196969 (N-[4-[ (3)

Name: CCT-196969 (N-[4-[ (3); MyBioSource
Brand: MyBioSource
SKU: MBS848774
Price: 245 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848774

CCT-196969 is a pan-Raf inhibitor, which inhibits B-Raf, BRafV600E and CRAF with IC50s of 0.1, 0.04, and 0.01 uM, respectively. It is selective for RAFs, Src, LCK, and MAPKs in a panel of 63 kinases when used at a concentration of 1 uM. CCT-196969 inhibits… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

CCT-196969, Biochemical

Full Product Name

CCT-196969

Product Synonym Names

N-[4-[ (3; 4-dihydro-3-oxopyrido[2; 3-b]pyrazin-8-yl) oxy]-2-fluorophenyl]-N'-[3- (1; 1-dimethylethyl)-1-phenyl-1H-pyrazol-5-yl]-urea; CCT196969

Form/Format

Crystalline solid

Purity/Purification

>=98%

Preparation and Storage

Store at -20 degree C
Shelf life: ~36 months

Molecular Weight

513.5

Solubility

>25 mg/ml in DMSO

Molecular Formula

C??H??FN?O?

CAS Number

1163719-56-9

PubChem CID

42628843

SMILES

CC (C)(C)C1=NN (C (=C1)NC (=O)NC2=C (C=C (C=C2)OC3=C4C (=NC=C3)NC (=O)C=N4)F)C5=CC=CC=C5

InChi

InChI=1S/C27H24FN7O3/c1-27 (2,3)21-14-22 (35 (34-21)16-7-5-4-6-8-16)32-26 (37)31-19-10-9-17 (13-18 (19)28)38-20-11-12-29-25-24 (20)30-15-23 (36)33-25/h4-15H,1-3H3, (H,29,33,36)(H2,31,32,37)

InChi Key

KYYKGSDLXXKQCR-UHFFFAOYSA-N

Product Categories/Family for CCT-196969 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Kinase Inhibitors (A-Z); Biochemicals; Biochemicals (A-Z); Protein Tyrosine Kinase Inhibitors; Enzyme Inhibitors (A-Z)

Product References and Citations for CCT-196969 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/42628843

Other Notes

Small volumes of CCT-196969 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CCT-196969 purchase

MBS848774 is a biochemical targeting CCT-196969.