CEP-28122 ((1S)

Name: CEP-28122 ((1S); MyBioSource
Brand: MyBioSource
SKU: MBS848777
Price: 205 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848777

CEP-28122 is a highly potent and selective orally active inhibitor of anaplastic lymphoma kinase (ALK) (IC50 = 1.9 nM). Displays antitumor activity in experimental models of human cancers. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

CEP-28122, Biochemical

Full Product Name

CEP-28122

Product Synonym Names

(1S; 2S; 3R; 4R)-3-[[5-chloro-2-[[ (7S)-6; 7; 8; 9-tetrahydro-1-methoxy-7- (4-morpholinyl)-5H-benzocyclohepten-2-yl]amino]-4-pyrimidinyl]amino]-bicyclo[2.2.1]hept-5-ene-2-carboxamide; CEP28122

Form/Format

Crystalline solid

Purity/Purification

>=98% by HPLC

Preparation and Storage

Store at -20 degree C
Shelf life: ~36 months

Molecular Weight

539.1

Solubility

>30 mg/ml in DMSO

Molecular Formula

C??H??ClN?O?

CAS Number

1022958-60-6

PubChem CID

57325421

SMILES

COC1=C (C=CC2=C1CCC (CC2)N3CCOCC3)NC4=NC=C (C (=N4)NC5C6CC (C5C (=O)N)C=C6)Cl

InChi

InChI=1S/C28H35ClN6O3/c1-37-25-20-8-7-19 (35-10-12-38-13-11-35)6-4-16 (20)5-9-22 (25)32-28-31-15-21 (29)27 (34-28)33-24-18-3-2-17 (14-18)23 (24)26 (30)36/h2-3,5,9,15,17-19,23-24H,4,6-8,10-14H2,1H3, (H2,30,36)(H2,31,32,33,34)/t17-,18+,19+,23+,24-/m1/s1

InChi Key

LAJAFFLJAJMYLK-CVOKMOJFSA-N

Product Categories/Family for CEP-28122 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Kinase Inhibitors (A-Z); ALK (Anaplastic Lymphoma Kinase) Inhibitors; Focal Adhesion Kinase (FAK)Inhibitors; Biochemicals; Biochemicals (A-Z); Enzyme Inhibitors (A-Z)

Product References and Citations for CEP-28122 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/57325421

Other Notes

Small volumes of CEP-28122 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CEP-28122 purchase

MBS848777 is a biochemical targeting CEP-28122.