CEP-40783 (RXDX106)

Name: CEP-40783 (RXDX106); MyBioSource
Brand: MyBioSource
SKU: MBS848779
Price: 205 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848779

CEP-40783 (RDX-106) is a potent and selective inhibitor of AXL and c-Met with IC50 values of 7 nM and 12 nM, respectively. In AXL-transfected 293GT cells, CEP-40783 was 27-fold more active compared to recombinant enzyme with an IC50 value of 0.26 nM.… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

CEP-40783, Biochemical

Full Product Name

CEP-40783

Product Synonym Names

RXDX106; CEP40783; N-[4- (6; 7-Dimethoxyquinolin-4-yl) oxy-3-fluorophenyl]-3- (4-fluorophenyl)-2; 4-dioxo-1-propan-2-ylpyrimidine-5-carboxamide; RXDX-106

Form/Format

Crystalline solid

Purity/Purification

>=98% by HPLC

Preparation and Storage

Store at -20 degree C
Shelf life: ~36 months

Molecular Weight

588.56

Solubility

>5 mg/ml in DMSO

Molecular Formula

C??H??F?N?O?

CAS Number

1437321-24-8

PubChem CID

71576419

SMILES

CC (C)N1C=C (C (=O)N (C1=O)C2=CC=C (C=C2)F)C (=O)NC3=CC (=C (C=C3)OC4=C5C=C (C (=CC5=NC=C4)OC)OC)F

InChi

InChI=1S/C31H26F2N4O6/c1-17 (2)36-16-22 (30 (39)37 (31 (36)40)20-8-5-18 (32)6-9-20)29 (38)35-19-7-10-26 (23 (33)13-19)43-25-11-12-34-24-15-28 (42-4)27 (41-3)14-21 (24)25/h5-17H,1-4H3, (H,35,38)

InChi Key

FKCWHHYUMFGOPY-UHFFFAOYSA-N

Product Categories/Family for CEP-40783 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Kinase Inhibitors (A-Z); Biochemicals; Biochemicals (A-Z); CMet Kinase Inhibitors; Enzyme Inhibitors (A-Z); Axl Receptor Tyrosine Kinase Inhibitors

Product References and Citations for CEP-40783 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/71576419

Other Notes

Small volumes of CEP-40783 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CEP-40783 purchase

MBS848779 is a biochemical targeting CEP-40783.