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PFK-158

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848789

PFK158 is an inhibitor of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3; IC50 = 137 nM for human recombinant PFKFB3). Upon administration, PFK-158 binds to and inhibits the activity of PFKFB3, which leads to the inhibition of both the… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PFK-158, Biochemical
Full Product Name
PFK-158
Product Synonym Names
N4-isobutyl-N2- ( (2-phenylthiazol-4-yl) methyl) pyrimidine-2; 4-diamine
Form/Format
White to off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months
Molecular Weight
328.29
Solubility
>30 mg/ml in DMSO
Molecular Formula
C??H??F?N?O
CAS Number
1462249-75-7
PubChem CID
71730058
SMILES
C1=CC (=CC2=C1C=CC (=N2)C=CC (=O)C3=CC=NC=C3)C (F)(F)F
InChi
InChI=1S/C18H11F3N2O/c19-18 (20,21)14-3-1-12-2-4-15 (23-16 (12)11-14)5-6-17 (24)13-7-9-22-10-8-13/h1-11H/b6-5+
InChi Key
IAJOMYABKVAZCN-AATRIKPKSA-N

Product Categories/Family for PFK-158 biochemical

Biochemicals; Enzyme Inhibitors; Other Inhibitors; Enzyme Inhibitors (A-Z); Biochemicals (A-Z)

Structure of PFK-158 biochemical

PFK-158 Biochemical – Cat# MBS848789

Product References and Citations for PFK-158 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/71730058

Other Notes

Small volumes of PFK-158 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PFK-158 purchase

MBS848789 is a biochemical targeting PFK-158.
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