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MK-591 sodium salt

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848793

MK-0591 sodium is a potent and specific 5-Lipoxygenase-activating protein (FLAP) inhibitor with an IC50 of 1.6 nM in FLAP binding assay; it displays no inhibitory effect on 15-lipoxygenase and platelet 12-lipoxygenase and cyclooxygenase in human PMNLs;… More details

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Product Overview

Product Name
MK-591, Biochemical
Full Product Name
MK-591 sodium salt
Product Synonym Names
MK0591; Quiflapon sodium; 1H-Indole-2-propanoic acid; 1-[ (4-chlorophenyl) methyl]-3-[ (1; 1-dimethylethyl) thio]-alpha; alpha-dimethyl-5- (2-quinolinylmethoxy)-; sodium salt; L-686708
Form/Format
Crystalline solid
Purity/Purification
>=98%
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months
Molecular Weight
609.15
Solubility
>40 mg/ml in DMSO
Molecular Formula
C??H??ClN?NaO?S
CAS Number
147030-01-1
PubChem CID
23672584
SMILES
CC (C)(C)SC1=C (N (C2=C1C=C (C=C2)OCC3=NC4=CC=CC=C4C=C3)CC5=CC=C (C=C5)Cl)CC (C)(C)C (=O)[O-].[Na+]
InChi
InChI=1S/C34H35ClN2O3S.Na/c1-33 (2,3)41-31-27-18-26 (40-21-25-15-12-23-8-6-7-9-28 (23)36-25)16-17-29 (27)37 (20-22-10-13-24 (35)14-11-22)30 (31)19-34 (4,5)32 (38)39;/h6-18H,19-21H2,1-5H3, (H,38,39);/q;+1/p-1
InChi Key
YPURUCMVRRNPHJ-UHFFFAOYSA-M

Product Categories/Family for MK-591 biochemical

Enzyme Inhibitors; FLAP (5; Lipoxygenase; activating protein) Inhibitors; Enzyme Inhibitors (A-Z); Biochemicals; Biochemicals (A-Z)

Structure of MK-591 biochemical

MK-591 sodium salt Biochemical – Cat# MBS848793

Product References and Citations for MK-591 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/23672584#section=2D-Structure

Other Notes

Small volumes of MK-591 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MK-591 purchase

MBS848793 is a biochemical targeting MK-591. Also known as MK-591 sodium salt.
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