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CBR-5884

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848816

CBR-5884 is a potent and selective inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH) (IC50 = 33 uM) inhibiting serine synthesis from 3-phosphoglycerate in cells. CBR-5884 inhibits serine biosynthesis in cells with no effect on two other dehydrogenases,… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
CBR-5884, Biochemical
Full Product Name
CBR-5884
Product Synonym Names
5-[ (2-furanylcarbonyl) amino]-3-methyl-4-thiocyanato-2-thiophenecarboxylic acid; ethyl ester
Form/Format
Off-white solid
Purity/Purification
>=98%
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months
Molecular Weight
336.39
Solubility
>30 mg/ml in DMSO
Molecular Formula
C??H??N?O?S?
CAS Number
681159-27-3
PubChem CID
4674993
SMILES
CCOC (=O)C1=C (C (=C (S1)NC (=O)C2=CC=CO2)SC#N)C
InChi
InChI=1S/C14H12N2O4S2/c1-3-19-14 (18)11-8 (2)10 (21-7-15)13 (22-11)16-12 (17)9-5-4-6-20-9/h4-6H,3H2,1-2H3, (H,16,17)
InChi Key
QBVIRPJBDIZKBC-UHFFFAOYSA-N

Structure of CBR-5884 biochemical

CBR-5884 Biochemical – Cat# MBS848816

Product References and Citations for CBR-5884 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/4674993

Other Notes

Small volumes of CBR-5884 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CBR-5884 purchase

MBS848816 is a biochemical targeting CBR-5884.
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