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iCRT14

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848834

iCRT14 is a potent potent inhibitor of beta-catenin-responsive transcription (CRT) that inhibits Wnt signaling in a reporter assay in vitro (IC50 = 40.3 nM). It inhibits the interaction between beta-catenin and T cell factor 4 (Tcf4) in quantitative reporter… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
iCRT14, Biochemical
Full Product Name
iCRT14
Product Synonym Names
iCRT 14; Wnt inhibitor; 5-[[2; 5-dimethyl-1- (3-pyridinyl)-1H-pyrrol-3-yl]methylene]-3-phenyl-2; 4-thiazolidinedione; iCRT-14
Form/Format
Crystalline solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months
Molecular Weight
375.45
Solubility
~2 mg/ml in DMSO
Molecular Formula
C??H??N?O?S
CAS Number
677331-12-3
SMILES
O=C (S/C1=C\C2=C (C)N (C3=CN=CC=C3)C (C)=C2)N (C4=CC=CC=C4)C1=O
InChi
InChI=1S/C21H17N3O2S/c1-14-11-16 (15 (2)23 (14)18-9-6-10-22-13-18)12-19-20 (25)24 (21 (26)27-19)17-7-4-3-5-8-17/h3-13H,1-2H3/b19-12-
InChi Key
NCSHZXNGQYSKLR-UNOMPAQXSA-N

Structure of iCRT14 biochemical

Icrt14 Biochemical – Cat# MBS848834

Other Notes

Small volumes of iCRT14 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for iCRT14 purchase

MBS848834 is a biochemical targeting iCRT14.
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