TCE35031 (2-[[2- (2)

Name: TCE35031 (2-[[2- (2); MyBioSource
Brand: MyBioSource
SKU: MBS848870
Price: 205 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848870

TCE35031 is an analog of Thalidomide commonly used as a precursor to PROTACs (proteolysis-targeting chimera technologies) that hijack cereblon as the E3 ubiquitin ligase component. Supplied with a carboxylic acid functional handle at a position known not to… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

TCE35031, Biochemical

Full Product Name

TCE35031

Product Synonym Names

2-[[2- (2; 6-Dioxo-3-piperidinyl)-2; 3-dihydro-1; 3-dioxo-1H-isoindol-4-yl]oxy]acetic acid; Carboxylic acid-functionalized Thalidomide; cereblon ligand for PROTACs

Form/Format

Off-white solid

Purity/Purification

>=98% by HPLC

Preparation and Storage

Store at -20 degree C
Shelf life: ~36 months

Molecular Weight

332.26

Solubility

>30 mg/ml in DMSO

Molecular Formula

C??H??N?O?

CAS Number

1061605-21-7

PubChem CID

25015436

SMILES

C1CC (=O)NC (=O)C1N2C (=O)C3=C (C2=O)C (=CC=C3)OCC (=O)O

InChi

InChI=1S/C15H12N2O7/c18-10-5-4-8 (13 (21)16-10)17-14 (22)7-2-1-3-9 (12 (7)15 (17)23)24-6-11 (19)20/h1-3,8H,4-6H2, (H,19,20)(H,16,18,21)

InChi Key

ZVWIXIGBWIEDFO-UHFFFAOYSA-N

Product Categories/Family for TCE35031 biochemical

Biochemicals; Biochemicals (A-Z); Activators; Inducers; Agonists; Other Agonists

Product References and Citations for TCE35031 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/25015436

Other Notes

Small volumes of TCE35031 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TCE35031 purchase

MBS848870 is a biochemical targeting TCE35031.