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Brusatol

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848878

Brusatol is a quassinoid isolated from the Brucea javanica plant that has recently been shown to inhibit Nrf2 signaling, reduce tumor burden, and ameliorate chemoresistance in both in vitro and in vivo cancer models. Brusatol also inhibits c-Myc expression,… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Brusatol, Biochemical
Full Product Name
Brusatol
Product Synonym Names
(+)-Brusatol; (11beta; 12alpha; 15beta)-13; 20-Epoxy-3; 11; 12-trihydroxy-15-[ (3-methyl-1-oxo-2-buten-1-yl) oxy]-2; 16-dioxo-picras-3-en-21-oic acid methyl ester; NSC 172924; Yatansin
Form/Format
Crystalline solid
Purity/Purification
>=95% by HPLC
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months
Molecular Weight
520.53
Solubility
~5 mg/ml in DMSO
Molecular Formula
C??H??O??
CAS Number
14907-98-3
MDL Number
MFCD23726642
PubChem CID
73432
SMILES
CC1=C (C (=O)CC2 (C1CC3C45C2C (C (C (C4C (C (=O)O3)OC (=O)C=C (C)C)(OC5)C (=O)OC)O)O)C)O
InChi
InChI=1S/C26H32O11/c1-10 (2)6-15 (28)37-18-20-25-9-35-26 (20,23 (33)34-5)21 (31)17 (30)19 (25)24 (4)8-13 (27)16 (29)11 (3)12 (24)7-14 (25)36-22 (18)32/h6,12,14,17-21,29-31H,7-9H2,1-5H3/t12-,14+,17+,18+,19+,20+,21-,24-,25+,26-/m0/s1
InChi Key
ZZZYHIMVKOHVIH-VILODJCFSA-N

Product Categories/Family for Brusatol biochemical

Biochemicals; Enzyme Inhibitors; Other Inhibitors; Enzyme Inhibitors (A-Z); Biochemicals (A-Z)

Structure of Brusatol biochemical

Brusatol Biochemical – Cat# MBS848878

Product References and Citations for Brusatol biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/73432

Other Notes

Small volumes of Brusatol biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Brusatol purchase

MBS848878 is a biochemical targeting Brusatol.
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