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Halofuginone hydrobromide (RU-19110)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848881

Halofuginone is an an ATP-dependent inhibitor prolyl-tRNA synthetase (Ki of 18.3 nM). Halofuginone attenuates osteoarthritis (OA) by inhibition of TGF-beta activity. Blocks expression of MMP2 and inhibits ECM invasion in vitro and lung metastasis by bladder… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Halofuginone hydrobromide, Biochemical
Full Product Name
Halofuginone hydrobromide
Product Synonym Names
RU-19110; (2R*; 3S*)-7-Bromo-6-chloro-3-[3- (3-hydroxy-2-piperidinyl)-2-oxopropyl]-4-3H-quinazolinone hydrobromide
Form/Format
White solid
Purity/Purification
>=98%
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months
Molecular Weight
495.59
Solubility
>45 mg/ml in DMSO
Molecular Formula
C??H??BrClN?O?-HBr
CAS Number
64924-67-0
PubChem CID
400771
SMILES
C1CC (C (NC1)CC (=O)CN2C=NC3=CC (=C (C=C3C2=O)Cl)Br)O.Br
InChi
InChI=1S/C16H17BrClN3O3.BrH/c17-11-6-13-10 (5-12 (11)18)16 (24)21 (8-20-13)7-9 (22)4-14-15 (23)2-1-3-19-14;/h5-6,8,14-15,19,23H,1-4,7H2;1H/t14-,15+;/m0./s1
InChi Key
SJUWEPZBTXEUMU-LDXVYITESA-N

Product References and Citations for Halofuginone hydrobromide biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/400771

Other Notes

Small volumes of Halofuginone hydrobromide biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Halofuginone hydrobromide purchase

MBS848881 is a biochemical targeting Halofuginone hydrobromide.
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