Wedelolactone (7-Methoxy-5)

Name: Wedelolactone (7-Methoxy-5); MyBioSource
Brand: MyBioSource
SKU: MBS848946
Price: 205 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848946

Wedelolactone is a natural coumestan that irreversibly inhibits IKK in NF-kappaB signaling pathway. IKK phosphorylates the IkappaBalpha protein, which results in the degradation and dissociation of IkappaBalpha from NF-kappaB leading to NF-kappaB activation.… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Wedelolactone, Biochemical

Full Product Name

Wedelolactone

Product Synonym Names

7-Methoxy-5; 11; 12-trihydroxy-coumestan; 1; 8; 9-Trihydroxy-3-methoxycoumestan; 1; 8; 9-Trihydroxy-3-methoxy-6H-[1]benzofuro[3; 2-c]chromen-6-one 1; 8; 9-trihydroxy-3-methoxy-6H-benzofuro[3; 2-c][1]benzopyran-6-one; IKK inhibitor

Form/Format

Crystalline solid

Purity/Purification

>98%

Preparation and Storage

Store at -20 degree C
Shelf life: ~36 months

Molecular Weight

314.25

Solubility

~20 mg/ml in Ethanol
~30 mg/ml in DMSO and DMF

Molecular Formula

C??H??O?

CAS Number

524-12-9

PubChem CID

5281813

SMILES

COC1=CC (=C2C (=C1)OC (=O)C3=C2OC4=CC (=C (C=C43)O)O)O

InChi

InChI=1S/C16H10O7/c1-21-6-2-10 (19)14-12 (3-6)23-16 (20)13-7-4-8 (17)9 (18)5-11 (7)22-15 (13)14/h2-5,17-19H,1H3

InChi Key

XQDCKJKKMFWXGB-UHFFFAOYSA-N

Product Categories/Family for Wedelolactone biochemical

Biochemicals; Enzyme Inhibitors; NF; KB Pathway Inhibitors; Biochemicals (A-Z); Immunology; Inflammation; Apoptosis & Related Products; Caspase Inhibitors; Activators; Inducers; Agonists; AMPK Activators

Product References and Citations for Wedelolactone biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/5281813

Other Notes

Small volumes of Wedelolactone biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Wedelolactone purchase

MBS848946 is a biochemical targeting Wedelolactone.