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CAY10603

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848954

CAY10603 is a selective inhibitor of Histone deacetylase 6 (HDAC6). The IC50 for inhibition of HDAC6 is 2 pM, in vitro. CAY10603 inhibited growth of various pancreatic cell lines with IC50 values ranging from 0.1 uM to 1 uM. It induced apoptosis and inhibited… More details

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Product Overview

Product Name
CAY10603, Biochemical
Full Product Name
CAY10603
Product Synonym Names
HDAC6 Inhibitor; tert-butyl N-[4-[3-[[7- (hydroxyamino)-7-oxoheptyl]carbamoyl]-1; 2-oxazol-5-yl]phenyl]carbamate; tert-butyl N-[4-[3-[[7- (hydroxyamino)-7-oxoheptyl]carbamoyl]-1; 2-oxazol-5-yl]phenyl]carbamate; {4-[3- (6-Hydroxycarbamoylhexylcarbamoyl) isoxazol-5-yl]phenyl}carbamic acid tert-butyl ester; Histone Deacetylase Inhibitor VIII
Form/Format
Crystalline solid
Purity/Purification
>98%
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months
Molecular Weight
446.50
Solubility
~15 mg/ml in DMSO
Molecular Formula
C??H??N?O?
CAS Number
1045792-66-2
MDL Number
MFCD17010286
PubChem CID
24951314
SMILES
CC (C)(C)OC (=O)NC1=CC=C (C=C1)C2=CC (=NO2)C (=O)NCCCCCCC (=O)NO
InChi
InChI=1S/C22H30N4O6/c1-22 (2,3)31-21 (29)24-16-11-9-15 (10-12-16)18-14-17 (26-32-18)20 (28)23-13-7-5-4-6-8-19 (27)25-30/h9-12,14,30H,4-8,13H2,1-3H3, (H,23,28)(H,24,29)(H,25,27)
InChi Key
WWGBHDIHIVGYLZ-UHFFFAOYSA-N

Product Categories/Family for CAY10603 biochemical

Epigenetics; Eraser Enzymes; Cancer Research; Epigenetic Regulation; Eraser Enzymes; Histone Deacetylase (HDAC) Inhibitors; Biochemicals; Biochemicals (A-Z); Apoptosis & Related Products; Apoptosis Inducers; Epigenetic Modulators (A-Z); Anticancer Agents;

Structure of CAY10603 biochemical

CAY10603 Biochemical – Cat# MBS848954

Product References and Citations for CAY10603 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/24951314

Other Notes

Small volumes of CAY10603 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CAY10603 purchase

MBS848954 is a biochemical targeting CAY10603.
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