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TZ9

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848970

TZ9 is a triazine analogue inhibitor of human E2 ubiquitin-conjugating enzyme Rad6B/HHR6B. It docks to the Rad6B catalytic site. It inhibits Rad6B-induced histone H2A ubiquitination, downregulates intracellular beta-catenin, induces G2-M arrest and apoptosis… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
TZ9, Biochemical
Full Product Name
TZ9
Product Synonym Names
TZ9; (4-amino-6-anilino-1; 3; 5-triazin-2-yl) methyl 4-nitrobenzoate; (4-amino-6- (phenylamino)-1; 3; 5-triazin-2-yl) methyl 4-nitrobenzoate; Rad6 inhibitor; HHR6 inhibitor
Form/Format
A crystalline solid
Purity/Purification
>=98%
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months
Molecular Weight
366.33
Solubility
~30 mg/ml in DMSO and DMF
Molecular Formula
C??H??N?O?
CAS Number
1002789-86-7
PubChem CID
7593228
SMILES
C1=CC=C (C=C1)NC2=NC (=NC (=N2)N)COC (=O)C3=CC=C (C=C3)[N+] (=O)[O-]
InChi
InChI=1S/C17H14N6O4/c18-16-20-14 (21-17 (22-16)19-12-4-2-1-3-5-12)10-27-15 (24)11-6-8-13 (9-7-11)23 (25)26/h1-9H,10H2, (H3,18,19,20,21,22)
InChi Key
RRRDZFQRNJTKHL-UHFFFAOYSA-N

Product Categories/Family for TZ9 biochemical

Enzyme Inhibitors; Ubiquitin Proteasome Pathway Inhibitors; Biochemicals; Biochemicals (A-Z); Anticancer Agents; Apoptosis Inducers; Enzyme Inhibitors (A-Z)

Structure of TZ9 biochemical

TZ9 Biochemical – Cat# MBS848970

Product References and Citations for TZ9 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/7593228

Other Notes

Small volumes of TZ9 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TZ9 purchase

MBS848970 is a biochemical targeting TZ9.
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